El valor pronóstico de la resonancia magnética por difusión en recién nacidos con encefalopatía hipóxico isquémica
Palabras clave:
encefalopatía hipóxico isquémica, recien nacidos, poster, seram, EHIResumen
Objetivos
Una de las causas más frecuentes de parálisis cerebral durante la infancia es la encefalopatía debido a eventos hipóxicos durante el parto. La hipotermia terapéutica es el tratamiento estándar en neonatos con encefalopatía hipóxico-isquémica (EHI) severa o moderada en la mayoría de los países con alto nivel socio-económico. No obstante, a pesar de la hipotermia terapéutica un 30-70% de los neonatos con EHI moderada o severa fallecen o sobreviven con alteraciones neurológicas importantes.
Material y métodos
Desde mayo de 2009 hasta junio de 2013 117 recién nacidos a término con EHI ingresaron en la UCI neonatal del Hospital Universitario Puerta del Mar y fueron sometidos a hipotermia terapéutica (enfriamiento del cuerpo a una temperatura rectal de 33.5 ºC durante 72 horas). Todos los pacientes cumplieron los criterios de inclusión para hipotermia terapéutica y mostraron signos clínicos de encefalopatía moderada o severa: Hipotonía, reflejos anómalos, succión débil o convulsiones.
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